We have integrated Gene Set Control Analysis (GSCA) (Joshi et al. Exp Hematol. 2013. 41(4):354-66) within CODEX. This analysis provides a complementary computational approach to the routine Gene Ontology analysis.
For an inputted gene set, the GSCA web tool identifies over-represented overlaps between the gene set and TF target genes by performing a hyper-geometric test to uncover potential transcriptional regulators.
Citing this webtool