We have integrated Gene Set Control Analysis (GSCA) (Joshi et al. Exp Hematol. 2013. 41(4):354-66) within CODEX. This analysis provides a complementary computational approach to the routine Gene Ontology analysis.

For an inputted gene set, the GSCA web tool identifies over-represented overlaps between the gene set and TF target genes by performing a hyper-geometric test to uncover potential transcriptional regulators.

Citing this webtool

Joshi A. et.al., Gene Set Control Analysis (GSCA) predicts hematopoietic control mechanisms from genome-wide transcription factor binding data. Exp Hematol.